Genetic Aberrations and Interaction of <i>NEK2</i> and <i>TP53</i> Accelerate Aggressiveness of Multiple Myeloma-Reference-Cited by-同舟云学术

Genetic Aberrations and Interaction of NEK2 and TP53 Accelerate Aggressiveness of Multiple Myeloma

Published:2022-01-27 Issue:9 Volume:9 Page:2104491
ISSN:2198-3844
Container-title:Advanced Science
language:en
Short-container-title:Advanced Science

Author:

Feng Xiangling¹²³,Guo Jiaojiao¹²,An Gang⁴,Wu Yangbowen³,Liu Zhenhao¹⁵,Meng Bin¹²,He Nihan¹,Zhao Xinying³,Chen Shilian¹,Zhu Yinghong¹²,Xia Jiliang¹²,Li Xin⁶,Yu Zhiyong⁷,Li Ruixuan⁶,Ren Guofeng³,Chen Jihua³,Wu Minghua¹²,He Yanjuan¹,Qiu Lugui⁴,Zhou Jiaxi⁴,Zhou Wen¹²^ORCID

Affiliation:

1. State Key Laboratory of Experimental Hematology Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education Key Laboratory of Carcinogenesis National Health and Family Planning Commission; Department of Hematology Xiangya Hospital Central South University Changsha Hunan 410028 China

2. Cancer Research Institute School of Basic Medical Science Central South University 110 # Xiangya street Changsha Hunan 410028 China

3. Xiang Ya School of Public Health Central South University Changsha Hunan 410028 China

4. State Key Laboratory of Experimental Hematology Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Science & Peking Union Medical College Tianjin 300041 China

5. Shanghai Center for Bioinformation Technology Shanghai 201203 China

6. The third Xiangya Hospital of Central South University Changsha Hunan 410013 China

7. Department of Pathology Changsha eighth hospital Changsha Hunan 410199 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.202104491

Reference48 articles.

1. Multiple Myeloma

2. The multiple myelomas — current concepts in cytogenetic classification and therapy

3. The genetic architecture of multiple myeloma

4. Molecular pathogenesis of multiple myeloma and its premalignant precursor

5. A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

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