Colorectal Cancer Patient‐Derived 2D and 3D Models Efficiently Recapitulate Inter‐ and Intratumoral Heterogeneity

Author:

Zhao Yuanyuan1,Zhang Bing2,Ma Yiming3,Zhao Fuqiang4,Chen Jianan4,Wang Bingzhi5,Jin Hua1,Zhou Fulai1,Guan Jiawei1,Zhao Qian1,Wang Hongying3,Liu Qian4,Zhao Fangqing267,Wang Xia1ORCID

Affiliation:

1. School of Pharmaceutical Sciences Tsinghua University Beijing 100084 China

2. Beijing Institutes of Life Science Chinese Academy of Sciences University of Chinese Academy of Sciences Beijing 100101 China

3. State Key Laboratory of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 China

4. Department of Colorectal Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 China

5. Department of Pathology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 China

6. Key Laboratory of Systems Biology Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences Hangzhou 310024 China

7. Center for Excellence in Animal Evolution and Genetics Chinese Academy of Sciences Kunming 650223 China

Funder

National Key Research and Development Program of China

Natural Science Foundation of Beijing Municipality

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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