Cdyl Deficiency Brakes Neuronal Excitability and Nociception through Promoting Kcnb1 Transcription in Peripheral Sensory Neurons

Author:

Sun Zhao‐Wei12,Waybright Jarod M.3,Beldar Serap4,Chen Lu1,Foley Caroline A.3,Norris‐Drouin Jacqueline L.3,Lyu Tian‐Jie1,Dong Aiping4,Min Jinrong456,Wang Yu‐Pu1,James Lindsey I.3,Wang Yun17ORCID

Affiliation:

1. Neuroscience Research Institute and Department of Neurobiology School of Basic Medical Sciences Key Laboratory for Neuroscience Ministry of Education/National Health Commission and State Key Laboratory of Natural and Biomimetic Drugs Peking University Beijing 100083 China

2. Institute of Military Cognitive and Brain Sciences Academy of Military Medical Sciences Beijing 100039 China

3. Center for Integrative Chemical Biology and Drug Discovery Division of Chemical Biology and Medicinal Chemistry UNC Eshelman School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA

4. Structural Genomics Consortium University of Toronto 101 College Street Toronto Ontario M5G 1L7 Canada

5. Hubei Key Laboratory of Genetic Regulation and Integrative Biology School of Life Sciences Central China Normal University Wuhan Hubei 430079 China

6. Department of Physiology University of Toronto Toronto Ontario M5S 1A8 Canada

7. PKU‐IDG/McGovern Institute for Brain Research Peking University Beijing 100871 China

Funder

National Natural Science Foundation of China

National Institute on Drug Abuse

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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