Pharmacokinetics and Bioequivalence of Branded and Generic Formulations of Dofetilide 0.5-mg Capsules After Single-Dose Administration in Healthy Subjects

Author:

VanderLugt James T.1,Bon Charles2,Knuth Dean3,Schreiber Rhonda4,Ruff Michael D.4

Affiliation:

1. Jasper Clinic, Inc; Kalamazoo MI USA

2. Biostudy Solutions, LLC; Wilmington NC USA

3. MPI Research; Mattawan MI USA

4. Mayne Pharma, Inc.; Greenville NC USA

Funder

Mayne Pharma, Inc.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Reference29 articles.

1. Increasing prevalence of atrial fibrillation and flutter in the United States;Naccarelli;Am J Cardiol,2009

2. Increased heart rate is associated with higher mortality in patients with atrial fibrillation (AF): results from the Outcomes Registry for Better Informed Treatment of AF (ORBIT-AF);Steinberg;J Am Heart Assoc,2015

3. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (writing committee to revise the 2001 guidelines for the management of patients with atrial fibrillation);Fuster;Circulation,2006

4. writing on behalf of the 2006 ACC/AHA/ESC Guidelines for the Management of Patients With Atrial Fibrillation Writing Committee. 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (updating the 2006 guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines;Wann;Circulation,2011

5. Dofetilide, a new class III antiarrhythmic agent;Lenz;Pharmacotherapy,2000

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