Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA-Reference-Cited by-同舟云学术

Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA

Published:2022-11-09 Issue:1 Volume:3 Page:2200071
ISSN:2688-4046
Container-title:Small Science
language:en
Short-container-title:Small Science

Author:

Hashiba Kazuki¹^ORCID,Sato Yusuke²^ORCID,Taguchi Masamitsu¹,Sakamoto Sachiko¹,Otsu Ayaka¹,Maeda Yoshiki¹,Shishido Takuya¹,Murakawa Masao¹,Okazaki Arimichi¹,Harashima Hideyoshi²

Affiliation:

1. Nucleic Acid Medicine Business Division Nitto Denko Corporation 1-1-2, Shimohozumi Ibaraki Osaka 567-8680 Japan

2. Laboratory for Molecular Design of Pharmaceutics, Faculty of Pharmaceutical Sciences Hokkaido University Kita-12, Nishi-6 Kita-Ku Sapporo 060-0812 Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Wiley

Subject

General Earth and Planetary Sciences,General Environmental Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/smsc.202200071

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1. Intradermal Vaccinations With RNA Coding for TAA Generate CD8+ and CD4+ Immune Responses and Induce Clinical Benefit in Vaccinated Patients

2. Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination

3. A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis