Metabolite characterization of a novel anti-cancer agent, icotinib, in humans through liquid chromatography/quadrupole time-of-flight tandem mass spectrometry-Reference-Cited by-同舟云学术

Metabolite characterization of a novel anti-cancer agent, icotinib, in humans through liquid chromatography/quadrupole time-of-flight tandem mass spectrometry

Published:2011-07-06 Issue:15 Volume:25 Page:2131-2140
ISSN:0951-4198
Container-title:Rapid Communications in Mass Spectrometry
language:en
Short-container-title:Rapid Commun. Mass Spectrom.

Author:

Liu Dongyang¹,Jiang Ji¹,Zhang Li²,Tan Fenlai³,Wang Yingxiang³,Hu Pei¹

Affiliation:

1. Clinical Pharmacology Research Center at Peking Union Medical College Hospital and Chinese Academy of Medical Sciences; Beijing 100730 China

2. Department of Pulmonary Medicine at Peking Union Medical College Hospital and Chinese Academy of Medical Sciences; Beijing 100730 China

3. Zhejiang Beta Pharma Inc.; Zhejiang China

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/rcm.5061/fullpdf

Reference17 articles.

1. L. Zhang J. Jiang D. Y. Liu Y. Xia F. L. Tan Y. X. Wang D. Zhang P. Hu Poster Presentation at 13th World Conference On Lung Cancer, July 2009, San Francisco, CA

2. Metabolite identification of a new antitumor agent icotinib in rats using liquid chromatography/tandem mass spectrometry

3. Identification of the major metabolites of tectorigenin in rat bile by liquid chromatography combined with time-of-flight and ion trap tandem mass spectrometry

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Chemical Enhancement Effect of Icotinib–Au Complex Studied by Combined Density Functional Theory and Surface-Enhanced Raman Scattering;Langmuir;2021-10-27

2. Small Molecule Kinase Inhibitor Drugs (1995–2021): Medical Indication, Pharmacology, and Synthesis;Journal of Medicinal Chemistry;2021-10-08

3. Icotinib Induces Mechanism-Based Inactivation of Recombinant Human CYP3A4/5 Possibly via Heme Destruction by Ketene Intermediate;Drug Metabolism and Disposition;2021-07-26

4. Interpretation of MS–MS spectra of small-molecule signal transduction inhibitors using accurate-m/z data and m/z-shifts with stable-isotope-labeled analogues and metabolites;International Journal of Mass Spectrometry;2021-06

5. Overlap time is an independent risk factor of radiation pneumonitis for patients treated with simultaneous EGFR-TKI and thoracic radiotherapy;Radiation Oncology;2021-02-23