Pilot trials in thrombosis: Purpose and pitfalls

Author:

Ikesaka Rick12,Langlois Nicole2,Carrier Marc12,Kearon Clive3,Le Gal Grégoire12

Affiliation:

1. Division of Hematology; Department of Medicine; University of Ottawa; Ottawa ON Canada

2. Clinical Epidemiology Program; Ottawa Hospital Research Institute; Ottawa ON Canada

3. Division of Hematology and Thromboembolism; Department of Medicine and the Thrombosis and Atherosclerosis Research Institute; McMaster University; Hamilton ON Canada

Funder

University of Ottawa

CanVECTOR Network

Jack Hirsh Professorship

Heart and Stroke Foundation of Ontario

Heart and Stroke Foundation of Canada

Canadian Institutes of Health Research

Publisher

Wiley

Subject

Hematology

Reference21 articles.

1. National Institutes of Health Research involving human subjects, glossary https://humansubjects.nih.gov/glossary

2. Why most published research findings are false;Ioannidis;PLoS Med,2005

3. Increasing value and reducing waste in research design, conduct, and analysis;Ioannidis;Lancet,2014

4. A tutorial on pilot studies: the what, why and how;Thabane;BMC Med Res Methodol,2010

5. Defining feasibility and pilot studies in preparation for randomised controlled trials: development of a conceptual framework;Eldridge;PLoS ONE,2016

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1. Issues in Designing and Interpreting Small Clinical Trials;Canadian Journal of Cardiology;2021-09

2. Development and Evaluation of Advanced Image Analysis Techniques for Pediatric Deep Vein Thrombosis Imaging Scans;2019 IEEE 19th International Conference on Bioinformatics and Bioengineering (BIBE);2019-10

3. Preventing Venous Thromboembolism in Patients with Cancer;New England Journal of Medicine;2019-05-30

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