Rationally Engineering the Cofactor Specificity of <i>Lf</i> SDR1 for Biocatalytic Synthesis of the Key Intermediate of Telotristat Ethyl-Reference-Cited by-同舟云学术

Rationally Engineering the Cofactor Specificity of Lf SDR1 for Biocatalytic Synthesis of the Key Intermediate of Telotristat Ethyl

Author:

Li Hengyu¹,Zhang Wenhe¹,Che Changli¹,Wang Huibin²,Jia Yutian¹,Gao Xiao¹,Jia Xian³,Qin Bin⁴,You Song¹^ORCID

Affiliation:

1. School of Life Sciences and Biopharmaceutical Sciences Shenyang Pharmaceutical University 103 Wenhua Road Shenhe Shenyang 110016 P. R. China

2. Graduate School of Pharmaceutical Sciences The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-0033 Japan

3. School of Pharmaceutical Engineering Shenyang Pharmaceutical University 103 Wenhua Road Shenhe Shenyang 110016 P. R. China

4. Wuya College of Innovation Shenyang Pharmaceutical University 103 Wenhua Road Shenhe Shenyang 110016 P. R. China

Funder

National Natural Science Foundation of China

Liaoning Revitalization Talents Program

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Link

Reference35 articles.

3. H. Younus inBiocatalysis(Eds.: Q. Husain M. F. Ullah) Springer Nature Switzerland AG Gewerbestrasse Switzerland 2019 pp. 39–55;

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