Enzyme Engineering Enables Inversion of Substrate Stereopreference of the Halogenase WelO5*-Reference-Cited by-同舟云学术

Enzyme Engineering Enables Inversion of Substrate Stereopreference of the Halogenase WelO5*

Published:2022-11-18 Issue:24 Volume:14 Page:
ISSN:1867-3880
Container-title:ChemCatChem
language:en
Short-container-title:ChemCatChem

Author:

Voss Moritz¹^ORCID,Hüppi Sean¹²^ORCID,Schaub Daniela¹^ORCID,Hayashi Takahiro¹³^ORCID,Ligibel Mathieu⁴,Sager Emine⁴^ORCID,Schroer Kirsten⁴,Snajdrova Radka⁴^ORCID,Buller Rebecca¹^ORCID

Affiliation:

1. Competence Center for Biocatalysis Institute for Chemistry and Biotechnology Zurich University of Applied Sciences 8820 Wädenswil Switzerland

2. Department of Biotechnology Delft University of Technology 2629 HZ Delft The Netherlands

3. Science & Innovation Center Mitsubishi Chemical Corporation Aoba ward Yokohama Kanagawa 227-8502 Japan

4. Novartis Institutes for BioMedical Research Global Discovery Chemistry 4056 Basel Switzerland

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Paul Scherrer Institut

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cctc.202201115

Reference40 articles.

2. Recent Advances in Flavin-Dependent Halogenase Biocatalysis: Sourcing, Engineering, and Application

3. Development of Halogenase Enzymes for Use in Synthesis

4. Late-stage C–H functionalization offers new opportunities in drug discovery

5. Halogenase engineering and its utility in medicinal chemistry

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery and substrate specificity engineering of nucleotide halogenases;Nature Communications;2024-06-19

2. Biocatalytic enantioselective C(sp3)–H fluorination enabled by directed evolution of non-haem iron enzymes;Nature Synthesis;2024-04-26

3. Advances in Noncanonical Amino Acid Incorporation for Enzyme Engineering Applications;CHIMIA;2023-06-28

4. Halogenases for the synthesis of small molecules;Current Opinion in Green and Sustainable Chemistry;2023-06

5. Improving Enzyme Fitness with Machine Learning;CHIMIA;2023-03-29