Affiliation:
1. State Key Laboratory and Institute of Elemento-Organic Chemistry Frontiers Science Center for New Organic Matter College of Chemistry Haihe Laboratory of Sustainable Chemical Transformations Nankai University Tianjin 300071 China
2. Guangxi Key Laboratory of Electrochemical and Magneto-Chemical Functional Materials College of Chemistry and Bioengineering Guilin University of Technology Guilin 541004 China
Abstract
AbstractThe trans‐addition of intermetallic σ‐bonds (E−E′; E E’=Si, B, Se, P, Sn, etc.) across alkynes has emerged as an exceptionally atom‐economical means of constructing multi‐substituted alkenes, which readily transform into densely functionalized and biologically active compounds. Compared to the widely studied cis‐E−E’ additions, trans‐E−E’ additions remain a more challenging and underdeveloped area. In this article, recent advances in trans‐E−E’ additions are summarized, encompassing various interelement compounds such as Si−Si, B−B, Si−B, P−B, Se−B, and B−Sn. We aim to provide a deeper understanding of trans‐E−E’ additions and facilitate the further development of synthetic methodologies and applications of vicinally trans‐bismetallated alkenes.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Tianjin Municipality
National Key Research and Development Program of China