Expanding the Substrate Scope of Native Amine Dehydrogenases through <i>In Silico</i> Structural Exploration and Targeted Protein Engineering-Reference-Cited by-同舟云学术

Expanding the Substrate Scope of Native Amine Dehydrogenases through In Silico Structural Exploration and Targeted Protein Engineering

Published:2022-09-29 Issue:22 Volume:14 Page:
ISSN:1867-3880
Container-title:ChemCatChem
language:en
Short-container-title:ChemCatChem

Author:

Ducrot Laurine¹,Bennett Megan²,André‐Leroux Gwenaëlle³^ORCID,Elisée Eddy¹^ORCID,Marynberg Sacha¹,Fossey‐Jouenne Aurélie¹,Zaparucha Anne¹^ORCID,Grogan Gideon²^ORCID,Vergne‐Vaxelaire Carine¹^ORCID

Affiliation:

1. Génomique Métabolique Genoscope Institut François Jacob CEA CNRS Univ Evry Université Paris-Saclay 2 rue Gaston Crémieux 91057 Evry France

2. York Structural Biology Laboratory Department of Chemistry University of York Heslington York YO10 5DD UK

3. Université Paris-Saclay INRAE, MaIAGE 78352 Jouy-en-Josas France

Funder

Agence Nationale de la Recherche

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cctc.202200880

Reference71 articles.

1. Reductive Amination in the Synthesis of Pharmaceuticals

2. The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

3. Enzymes Applied to the Synthesis of Amines

5. Transaminases for industrial biocatalysis: novel enzyme discovery

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