Does the imbalance in the apolipoprotein E isoforms underlie the pathophysiological process of sporadic Alzheimer's disease?

Author:

Lozupone Madia1ORCID,Imbimbo Bruno Pietro2,Balducci Claudia3,Lo Vecchio Filomena4,Bisceglia Paola4,Latino Raffaela Rita5,Leone Maurizio5,Dibello Vittorio6,Solfrizzi Vincenzo7,Greco Antonio4,Daniele Antonio89,Watling Mark10,Seripa Davide11,Panza Francesco12ORCID

Affiliation:

1. Neurodegenerative Disease Unit Department of Basic Medicine Neuroscience and Sense Organs University of Bari Aldo Moro Bari Italy

2. Department of Research and Development Chiesi Farmaceutici Parma Italy

3. Department of Neuroscience Istituto di Ricerche Farmacologiche “Mario Negri” IRCCS Milan Italy

4. Research Laboratory Complex Structure of Geriatrics Department of Medical Sciences Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo Foggia Italy

5. Complex Structure of Neurology Department of Medical Sciences Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo Foggia Italy

6. Department of Orofacial Pain and Dysfunction Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and Vrije Universiteit Amsterdam Amsterdam the Netherlands

7. “Cesare Frugoni” Internal and Geriatric Medicine and Memory Unit University of Bari “Aldo Moro Bari Italy

8. Department of Neuroscience Catholic University of Sacred Heart Rome Italy

9. Neurology Unit IRCCS Fondazione Policlinico Universitario A. Gemelli Rome Italy

10. CNS & Pain Department TranScrip Ltd Reading UK

11. Hematology and Stem Cell Transplant Unit “Vito Fazzi” Hospital Lecce Italy

12. Unit of Research Methodology and Data Sciences for Population Health National Institute of Gastroenterology “Saverio de Bellis,” Research Hospital Castellana Grotte Bari Italy

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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