MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma
Author:
Publisher
Wiley
Subject
Oncology,Hematology,Pediatrics, Perinatology and Child Health
Reference22 articles.
1. MGMT gene silencing and benefit from temozolomide in glioblastoma;Hegi;N Engl J Med,2005
2. CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas;Paz;Clin Cancer Res,2004
3. Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide;Hegi;Clin Cancer Res,2004
4. . Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents;Esteller;N Engl J Med,2000
5. Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent;Ochs;Cancer Res,2000
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