[18F]Nifene test-retest reproducibility in first-in-human imaging of α4β2* nicotinic acetylcholine receptors

Author:

Lao Patrick J.12ORCID,Betthauser Tobey J.12,Tudorascu Dana L.3,Barnhart Todd E.1,Hillmer Ansel T.4,Stone Charles K.5,Mukherjee Jogeshwar6,Christian Bradley T.127

Affiliation:

1. Department of Medical Physics; University of Wisconsin-Madison; Madison Wisconsin 53705

2. Waisman Laboratory for Brain Imaging and Behavior; Madison Wisconsin 53705

3. Department of Medicine; Biostatistics, Psychiatry, and Clinical and Translational Science, University of Pittsburgh; Pittsburgh Pennsylvania 15213

4. Department of Radiology and Biomedical Imaging; and Psychiatry, Yale University; New Haven Connecticut 06520

5. Department of Medicine; University of Wisconsin School of Medicine and Public Health; Madison Wisconsin 53705

6. Department of Radiological Sciences; University of California-Irvine; Irvine California 92697

7. Department of Psychiatry; University of Wisconsin-Madison; Madison Wisconsin 53705

Funder

National Institutes of Health

National Institute of Child Health and Human Development

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience

Reference23 articles.

1. British Standards Institution 1994 Accuracy (trueness and precision) of measurement methods and results: Basic methods for the determination of repeatability and reproducibility of a standard measurement method

2. Cigarette smoking saturates brain α4β2 nicotinic acetylcholine receptors;Brody;Archives of General Psychiatry,2006

3. Evaluation of [18F]Nifene biodistribution and dosimetry based on whole-body PET imaging of mice;Constantinescu;Nuclear Medicine and Biology,2013

4. Improved kinetic analysis of dynamic PET data with optimized HYPR-LR;Floberg;Medical Physics,2012

5. Neuronal nicotinic receptors: From structure to pathology;Gotti;Progress in Neurobiology,2004

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