Determination of kinetic parameters and structure-activity relationships of ginsenosides as inhibitors of cyclin-dependent kinase 5/p25 using ultra-pressure liquid chromatography with triple quadrupole tandem mass spectrometry

Author:

Chen Ning12,Yang Hongmei1,Niu Jun1,Liu Shuying13

Affiliation:

1. Changchun Institute of Applied Chemistry, Chinese Academy of Sciences; Changchun Center of Mass Spectrometry; 5625# Renmin Street Changchun 130022 China

2. Graduate School of Chinese Academy of Sciences; Beijing 100039 China

3. Changchun University of Chinese Medicine; Changchun 130117 China

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference40 articles.

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3. A scintillation proximity assay for studying inhibitors of human tau protein kinase II/cdk5 using a 96-well format;Evans;J. Biochem. Biophys. Methods,2002

4. Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease;Bancher;Brain Res.,1989

5. Molecular analysis of neurofibrillary degeneration in Alzheimer's disease. An immunohistochemical study;Bondareff;Am. J. Pathol.,1990

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