Maduramicin induces apoptosis and necrosis, and blocks autophagic flux in myocardial H9c2 cells

Author:

Chen Xin123ORCID,Chen Long1ORCID,Jiang Shanxiang2,Huang Shile34ORCID

Affiliation:

1. Postdoctoral Mobile Station of Biology, College of Life Sciences; Nanjing Normal University; Nanjing Jiangsu Province 210023 People's Republic of China

2. Laboratory of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine; Nanjing Agricultural University; Nanjing Jiangsu Province 210095 People's Republic of China

3. Department of Biochemistry and Molecular Biology; Louisiana State University Health Sciences Center; Shreveport LA 71130-3932 USA

4. Feist-Weiller Cancer Center; Louisiana State University Health Sciences Center; Shreveport LA 71130-3932 USA

Funder

National Natural Science Foundation of China

Nanjing Agricultural University

National Cancer Institute

American Cancer Society

Feist-Weiller Cancer Center, Louisiana State University Health Sciences Center

Publisher

Wiley

Subject

Toxicology

Reference41 articles.

1. Cardiomyopathy of ruminants induced by the litter of poultry fed on rations containing the ionophore antibiotic, maduramicin. II. Macropathology and histopathology;Bastianello;Onderstepoort Journal of Veterinary Research,1995

2. Salinomycin potentiates the cytotoxic effects of TRAIL on glioblastoma cell lines;Calzolari;PLoS One,2014

3. Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cells;Chen;Cancer Prevention Research,2012

4. Maduramicin inhibits proliferation and induces apoptosis in myoblast cells;Chen;PLoS One,2014

5. Quantitation of apoptosis and necrosis by annexin V Binding, propidium iodide uptake, and flow cytometry;Crowley;Cold Spring Harbor Protocols,2016

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