Analytical strategies to include the X‐chromosome in variance heterogeneity analyses: Evidence for trait‐specific polygenic variance structure

Author:

Deng Wei Q.1,Mao Shihong2,Kalnapenkis Anette3,Esko Tõnu34,Mägi Reedik3,Paré Guillaume25ORCID,Sun Lei16ORCID

Affiliation:

1. Department of Statistical Sciences, Faculty of Arts and ScienceUniversity of Toronto Toronto Canada

2. Department of Pathology and Molecular Medicine, Population Health Research InstituteHamilton Health Sciences and McMaster University Hamilton Canada

3. Estonian Genome Center, Institute of GenomicsUniversity of Tartu Tartu Estonia

4. Program in Medical and Population GeneticsBroad Institute Cambridge Massachusetts

5. Department of Pathology and Molecular MedicineMcMaster University Hamilton Canada

6. Division of Biostatistics, Dalla Lana School of Public HealthUniversity of Toronto Toronto Canada

Funder

Natural Sciences and Engineering Research Council of Canada

Canadian Institutes of Health Research

Eesti Teadusagentuur

European Regional Development Fund

Publisher

Wiley

Subject

Genetics(clinical),Epidemiology

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