Population Pharmacokinetics and Exploratory Exposure-Response Relationships of Diazepam in Children Treated for Status Epilepticus

Author:

Ku Lawrence C.12,Hornik Christoph P.12,Beechinor Ryan J.3,Chamberlain James M.4,Guptill Jeffrey T.1,Harper Barrie1,Capparelli Edmund V.5,Martz Karen6,Anand Ravinder6,Cohen-Wolkowiez Michael12,Gonzalez Daniel3,

Affiliation:

1. Duke Clinical Research Institute; Duke University School of Medicine; Durham North Carolina USA

2. Department of Pediatrics; Duke University School of Medicine; Durham North Carolina USA

3. Division of Pharmacotherapy and Experimental Therapeutics; UNC Eshelman School of Pharmacy; The University of North Carolina at Chapel Hill; Chapel Hill North Carolina USA

4. Division of Emergency Medicine; Children's National Medical Center; Washington DC USA

5. Skaggs School of Pharmacy and Pharmaceutical Sciences; University of California, San Diego; California USA

6. Emmes Corporation; Rockville Maryland USA

Funder

National Institute of Child Health and Human Development

National Center for Advancing Translational Sciences

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

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