Thyrocyte‐specific deletion of insulin and IGF‐1 receptors induces papillary thyroid carcinoma‐like lesions through EGFR pathway activation

Author:

Ock Sangmi1,Ahn Jihyun1,Lee Seok Hong1,Kim Hyun Min1,Kang Hyun2,Kim Young‐Kook3,Kook Hyun4,Park Woo Jin5,Kim Shin6,Kimura Shioko7,Jung Chan Kwon8,Shong Minho9,Holzenberger Martin10,Abel E. Dale11,Lee Tae Jin12,Cho Bo Youn1,Kim Ho‐Shik13,Kim Jaetaek1ORCID

Affiliation:

1. Division of Endocrinology and Metabolism, Department of Internal MedicineCollege of Medicine, Chung‐Ang University Seoul Korea

2. Department of AnesthesiologyCollege of Medicine, Chung‐Ang University Seoul Korea

3. Department of BiochemistryChonnam National University Medical School Gwangju Korea

4. Department of Pharmacology and Medical Research Center for Gene RegulationChonnam National University Medical School Gwangju Korea

5. Department of Life ScienceGwangju Institute of Science and Technology Gwangju Korea

6. Department of ImmunologyKeimyung University School of Medicine Daegu Korea

7. Laboratory of Metabolism, National Cancer InstituteNational Institutes of Health Bethesda MD USA

8. Department of Hospital PathologyCollege of Medicine, The Catholic University of Korea Seoul Korea

9. Research Center for Endocrine and Metabolic Diseases, Department of Internal MedicineChungnam National University Daejeon Korea

10. INSERM and Sorbonne UniversitySaint‐Antoine Research Center Paris France

11. Fraternal Order of Eagles Diabetes Research Center and Division of Endocrinology and MetabolismUniversity of Iowa Carver College of MedicineIowa CityIA, USA

12. Department of Pathology, College of MedicineChung‐Ang UniversitySeoulKorea

13. Department of BiochemistryCollege of Medicine, The Catholic University of KoreaSeoulKorea

Funder

National Research Foundation of Korea

Publisher

Wiley

Subject

Cancer Research,Oncology

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