Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia

Author:

Hatsukawa Hiroatsu1,Ishikawa Masaaki1ORCID,Hirai Tomoyuki2,Endo Kazuo2,Saito Emiko2,Matsumoto Hirotaka2,Okazaki Kouya2

Affiliation:

1. Department of Otolaryngology, Head and Neck Surgery Hyogo Prefectural Amagasaki General Medical Center Amagasaki Japan

2. Department of Respiratory Medicine Hyogo Prefectural Amagasaki General Medical Center Amagasaki Japan

Abstract

AbstractWe aimed to elucidate details of comorbid chronic rhinosinusitis (CRS) in chronic eosinophilic pneumonia (CEP) under the collaboration between otolaryngologists and pulmonologists in a prospective study. The CEP diagnosis was performed by pulmonologists based on clinical symptoms, laboratory findings, and/or eosinophilia detected in bronchoalveolar lavage. All patients were referred to otolaryngologists before undergoing oral corticosteroid treatment for CEP. Ten CEP cases visited to otolaryngologists. All cases showed bilateral sinonasal inflammation in computed tomography (CT), indicating comorbid CRS. Nasal polyps (NPs) were observed in 50% of patients on endoscopy. Eighty percent of patients were diagnosed with eosinophilic CRS. In blood eosinophil levels and the mucosal eosinophil count, there were no significant differences between CRS without and with NPs. In Lund–Mackay CT total scores, among‐individual variability was observed in CRS with NPs. The collaboration revealed blood/sinonasal eosinophilia and the variability in Lund–Mackay CT total scores as remarkable findings about the comorbid CRS.

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Pulmonology for the rhinologist;Current Opinion in Otolaryngology & Head & Neck Surgery;2023-11-15

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