Apoptin causes apoptosis in <scp>HepG</scp> ‐2 cells via Ca <sup>2+</sup> imbalance and activation of the mitochondrial apoptotic pathway-Reference-Cited by-同舟云学术

Apoptin causes apoptosis in HepG ‐2 cells via Ca ²⁺ imbalance and activation of the mitochondrial apoptotic pathway

Published:2022-12-14 Issue:7 Volume:12 Page:8306-8318
ISSN:2045-7634
Container-title:Cancer Medicine
language:en
Short-container-title:Cancer Medicine

Author:

Yu Xiaoyang¹^ORCID,Wang Tongxing²,Li Yue¹,Li Yiquan¹,Bai Bing¹,Fang Jinbo¹,Han Jicheng¹,Li Shanzhi¹,Xiu Zhiru¹,Liu Zirui²,Yang Xia¹,Li Yaru¹,Zhu Guangze¹,Jin Ningyi¹²³,Shang Chao²,Li Xiao¹²,Zhu Yilong¹

Affiliation:

1. Academicians Workstation of Jilin Province Changchun University of Chinese Medicine Changchun China

2. Changchun Veterinary Research Institute Chinese Academy of Agricultural Sciences Changchun China

3. Jiangsu Co‐innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses Yangzhou China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cam4.5528

Reference42 articles.

1. Chicken anemia virus causes apoptosis of thymocytes after in vivo infection and of cell lines after in vitro infection

2. Cancer-selective therapy of the future: Apoptin and its mechanism of action

3. The Chicken Anemia Virus-Derived Protein Apoptin Requires Activation of Caspases for Induction of Apoptosis in Human Tumor Cells

4. Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent

5. Cancer-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur77-dependent pathway

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