An alkaline comet assay study on the antimalarial drug atovaquone in human peripheral blood lymphocytes: a study based on clinically relevant concentrations

Author:

Dinter Domagoj1,Gajski Goran2,Garaj-Vrhovac Vera2

Affiliation:

1. Pliva Croatia Ltd; Oral Solid Forms; 10000; Zagreb; Croatia

2. Institute for Medical Research and Occupational Health; Mutagenesis Unit; 10000; Zagreb; Croatia

Publisher

Wiley

Subject

Toxicology

Reference47 articles.

1. Genotoxic evaluation of the antimalarial drug, fansidar, in cultured human lymphocytes;Abou-Eisha;Cell Biol. Toxicol.,2004

2. Antimalarial drug toxicity: a review;AlKadi;Chemotherapy,2007

3. Atovaquone: a new antipneumocystis agent;Artymowicz;Clin. Pharm.,1998

4. Antiparasitic agent atovaquone;Baggish;Antimicrob. Agents Chemother.,2002

5. Causal prophylactic efficacy of atovaquone-proguanil (Malarone) in a human challenge model;Berman;Trans. R. Soc. Trop. Med. Hyg.,2001

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