Characterization of [123I]FP-CIT binding to the dopamine transporter in the striatum of tree shrews by quantitativein vitroautoradiography

Author:

Geisler Stefanie1,Beindorff Nicola2,Cremer Markus1,Hoffmann Kerstin3,Brenner Winfried2,Cumming Paul45,Meyer Philipp T.6,Langen Karl-Josef17,Fuchs Eberhard38,Buchert Ralph2

Affiliation:

1. Forschungszentrum Jülich GmbH - Institute of Neuroscience and Medicine; Jülich Germany

2. Department of Nuclear Medicine; Charité - Universitätsmedizin Berlin; Berlin Germany

3. German Primate Center; Göttingen Germany

4. Department of Nuclear Medicine; Friedrich-Alexander University; Erlangen/Nürnberg Germany

5. Department of Neuroscience and Pharmacology; University of Copenhagen; Denmark

6. Department of Nuclear Medicine; University of Freiburg; Freiburg Germany

7. Department of Nuclear Medicine; University of Aachen; Aachen Germany

8. Department of Neurology; University Medical Center, Georg-August-University Göttingen; Göttingen Germany

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience

Reference42 articles.

1. SPECT imaging of dopamine transporters in human brain with iodine-123-fluoroalkyl analogs of beta-CIT;Abi-Dargham;J Nucl Med,1996

2. Reproducibility of 11C-raclopride binding in the rat brain measured with the microPET R4: Effects of scatter correction and tracer specific activity;Alexoff;J Nucl Med,2003

3. Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT SPECT imaging: The [123I]-FP-CIT study group;Benamer;Mov Disord,2000

4. [123I]FP-CIT binds to the dopamine transporter as assessed by biodistribution studies in rats and SPECT studies in MPTP-lesioned monkeys;Booij;Synapse,1997

5. Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain;Boyson;J Neurosci,1986

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