Thrombocytopenia with Impella: Not a HIT-Reference-Cited by-同舟云学术

Thrombocytopenia with Impella: Not a HIT

Published:2023-02 Issue:2 Volume:101 Page:324-325
ISSN:1522-1946
Container-title:Catheterization and Cardiovascular Interventions
language:en
Short-container-title:Cathet Cardio Intervent

Author:

Seto Arnold H.¹²³^ORCID,Kern Morton J.¹³^ORCID

Affiliation:

1. Department of Medicine VA Long Beach Healthcare System Long Beach California USA

2. Department of Medicine Charles R. Drew University of Medicine and Science Los Angeles California USA

3. Department of Medicine University of California Irvine California USA

Abstract

Key Points

The Impella percutaneous microaxial ventricular assist device provides significant ventricular unloading, but at the cost of increased major bleeding, hemolysis, and thrombocytopenia.

The present study shows that nearly all patients develop thrombocytopenia within 7 days of Impella insertion with 81% having a >50% decrease. Platelet recovery occurs following device removal.

Recognition of Impella‐related thrombocytopenia can reduce the concern for heparin‐induced thrombocytopenia and avoid the potential risks of direct thrombin inhibitors.

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine,Radiology, Nuclear Medicine and imaging,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ccd.30588

Reference5 articles.

1. Heparin-Induced Thrombocytopenia

2. Incidence and severity of thrombocytopenia associated with use of intravascular microaxial ventricular assist devices for treatment of cardiogenic shock

3. Incidence and Timing of Thrombocytopenia in Patients Receiving Impella Ventricular Assist Device Support

4. Heparin-Induced Thrombocytopenia under Mechanical Circulatory Support by Large Impella for Acute Cardiogenic Shock

5. The Predictive Value of the 4Ts and HEP Score at Recommended Cutoffs in Patients With Mechanical Circulatory Support Devices