Metformin prevents hepatocellular carcinoma development by suppressing hepatic progenitor cell activation in a rat model of cirrhosis

Author:

DePeralta Danielle K.1,Wei Lan1,Ghoshal Sarani1,Schmidt Benjamin1,Lauwers Gregory Y.2,Lanuti Michael3,Chung Raymond T.4,Tanabe Kenneth K.1,Fuchs Bryan C.1

Affiliation:

1. Division of Surgical Oncology; Massachusetts General Hospital Cancer Center and Harvard Medical School; Boston Massachusetts

2. Department of Pathology; Massachusetts General Hospital Cancer Center and Harvard Medical School; Boston Massachusetts

3. Division of Thoracic Surgery; Massachusetts General Hospital Cancer Center and Harvard Medical School; Boston Massachusetts

4. Gastrointestinal Unit, Department of Medicine; Massachusetts General Hospital and Harvard Medical School; Boston Massachusetts

Funder

National Institutes of Health

Massachusetts General Hospital Department of Surgery

Publisher

Wiley

Subject

Cancer Research,Oncology

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