A novel blueprint for ‘top down’ differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia

Author:

Herfs Michael12,Vargas Sara O3,Yamamoto Yusuke4,Howitt Brooke E1,Nucci Marisa R1,Hornick Jason L1,Mckeon Frank D45,Xian Wa16,Crum Christopher P1

Affiliation:

1. Division of Women's and Perinatal Pathology, Department of Pathology; Brigham and Women's Hospital; Boston MA USA

2. Department of Pathology, GIGA-Cancer; University of Liège; Liège Belgium

3. Department of Pathology; Children's Hospital; Boston MA USA

4. Genome Institute of Singapore, A-STAR; Singapore

5. Department of Cell Biology; Harvard Medical School; Boston MA USA

6. Institute of Medical Biology, A-STAR; Singapore

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference22 articles.

1. Original site of cervical carcinoma; topographical relationship of carcinoma of the cervix to the external os and to the squamocolumnar junction;Marsh;Obstet Gynecol,1956

2. Cervical intraepithelial neoplasia;Richart;Pathol Annu,1973

3. Role of hormone cofactors in the human papillomavirus-induced carcinogenesis of the uterine cervix;Delvenne;Mol Cell Endocrinol,2007

4. Audit of the histological definition of cervical transformation zone;Mukonoweshuro P;J Clin Pathol,2005

5. Microglandular hyperplasia: a model for the de novo emergence and evolution of endocervical reserve cells;Witkiewicz;Hum Pathol,2005

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