Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV‐1 protease by enhanced conformational sampling-Reference-Cited by-同舟云学术

Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV‐1 protease by enhanced conformational sampling

Published:2018-10-30 Issue:12 Volume:86 Page:1294-1305
ISSN:0887-3585
Container-title:Proteins: Structure, Function, and Bioinformatics
language:en
Short-container-title:Proteins

Author:

Chen Jianzhong¹²^ORCID,Peng Cheng²³,Wang Jinan²,Zhu Weiliang²

Affiliation:

1. School of Science, Shandong Jiaotong University Jinan China

2. Drug Discovery and Design CenterCAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences Shanghai China

3. School of Chemistry, University of Chinese Academy of Sciences Beijing China

Funder

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prot.25610

Reference90 articles.

1. HIV drug development: the next 25 years