Residue-level determinants of angiopoietin-2 interactions with its receptor Tie2-Reference-Cited by-同舟云学术

Residue-level determinants of angiopoietin-2 interactions with its receptor Tie2

Published:2018-12-21 Issue:3 Volume:87 Page:185-197
ISSN:0887-3585
Container-title:Proteins: Structure, Function, and Bioinformatics
language:en
Short-container-title:Proteins

Author:

Bakhman Anna¹,Rabinovich Eitan²,Shlamkovich Tomer²,Papo Niv²^ORCID,Kosloff Mickey¹^ORCID

Affiliation:

1. Department of Human Biology, Faculty of Natural Sciences; University of Haifa; Haifa Israel

2. Department of Biotechnology Engineering and the National Institute of Biotechnology in the Negev; Ben-Gurion University of the Negev; Beer-Sheva Israel

Funder

European Research Council “Ideas program” ERC-2013-StG

Israel Ministry of Science, Technology and Space, Israel, and the Italian Ministry of Foreign Affairs

Israel Science Foundation

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/prot.25638/fullpdf

Reference57 articles.

1. Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1;Gale;Dev Cell,2002

2. Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling;Eklund;Exp Cell Res,2006

3. Angiopoietin-2 is critical for cytokine-induced vascular leakage;Benest;PLoS one,2013

4. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis;Maisonpierre;Science,1997

5. Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway;Kim;Oncogene,2000

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