Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX‐2/5‐LOX inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX‐2/5‐LOX inhibitors

Published:2020-07-21 Issue:11 Volume:353 Page:2000027
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch Pharm

Author:

Shaaban Mohamed A.¹,Kamal Aliaa M.¹²,Faggal Samar I.¹,Farag Nahla A.³,Aborehab Nora M.⁴,Elsahar Ayman E.⁵,Mohamed Khaled O.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy Cairo University Cairo Egypt

2. Department of Organic Chemistry, Faculty of Pharmacy October University for Modern Science and Arts (MSA) Giza Egypt

3. Department of Pharmaceutical Chemistry, Faculty of Pharmacy Misr International University Cairo Egypt

4. Department of Biochemistry, Faculty of Pharmacy October University for Modern Science and Arts (MSA) Giza Egypt

5. Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University Cairo Egypt

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ardp.202000027

Reference53 articles.

1. New Trends in Dual 5-LOX / COX Inhibition

2. Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy? 1 1Abbreviations: NSAIDs, nonsteroidal anti-inflammatory drugs; COX, cyclooxygenase; LT, leukotriene; 5-LOX, 5-lipoxygenase; PG, prostaglandin; DFU, 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsuphonyl)-phenyl-2(5H)-furanone; and DFP, diisopropyl fluorophosphate.

3. Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology

4. Pharmacodynamic of cyclooxygenase inhibitors in humans

5. Nonsteroidal Anti‐Inflammatory Drugs, Gastroprotection, and Benefit–Risk

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2. Anti-Inflammatory Activity of Pyrazolo[1,5-a]quinazolines;Molecules;2024-05-21

3. Exploring of novel oxazolones and imidazolones as anti-inflammatory and analgesic candidates with cyclooxygenase inhibitory action;Future Medicinal Chemistry;2024-04-19

4. Development of Novel Pyrrole Derivatives and Their Cinnamic Hybrids as Dual COX-2/LOX Inhibitors;Molecules;2023-12-05

5. Pyrazolo[5,1‐b]quinazolines and Their Bis‐analogues Linked to Different Spacers: Regioselective Synthesis, Antibacterial Screening and SwissADME Prediction Study;ChemistrySelect;2023-06-09

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