Tubercular meningitis and cortical venous thrombosis: A rare but potentially lethal combination—A case report and literature review

Author:

Mehta Kahan1,Chandrani Naazmin2,Shah Ishani1,Mehta Samir3,Omar Mohamed A.4ORCID

Affiliation:

1. Department of Internal Medicine GMERS Medical College, and Hospital Vadodara India

2. Department of General Medicine Baroda Medical College Vadodara India

3. Department of Medicine B.J Medical College Ahmedabad India

4. Faculty of Health Sciences University of Nairobi Nairobi Kenya

Abstract

Key Clinical MessageCortical venous thrombosis is a rare but severe complication of TBM that requires a high index of suspicion for early diagnosis. The treatment of CVT in TBM is based on anticoagulant therapy, which is known to improve the outcomes of the patients.AbstractThe case report describes an 18‐year‐old male in India with symptoms of tubercular meningitis complicated by cortical venous thrombosis. Tubercular meningitis is a rare but severe form of meningitis caused by tuberculosis bacteria and is a significant public health concern in India. The patient presented to the emergency department with a history of fever, headache, and vomiting for the past month, with a positive Mycobacterium tuberculosis test. The patient was started on standard antitubercular therapy and was diagnosed with cortical venous thrombosis via an MRI scan. Treatment included antitubercular therapy, anticoagulation therapy, dexamethasone, and antiemetic drugs. The patient's symptoms improved over 2 weeks of therapy. The case highlights the importance of early detection, treatment, and prevention strategies, such as the National Tuberculosis elimination program, in controlling the spread of tuberculosis in India. It also emphasizes the importance of close monitoring for complications in patients with tubercular meningitis, such as cortical venous thrombosis, which can be life‐threatening.

Publisher

Wiley

Subject

General Medicine

Reference10 articles.

1. More than 40% of the population in India carry tuberculosis infection in their body but only 10% get TB disease: Chief Medical Officer.https://pib.gov.in/PressReleasePage.aspx?PRID=1808092; 2015Press Information Bureau. National Tuberculosis Institute.

2. Dilatation of deep medullary veins in cortical venous occlusion due to focal tuberculous leptomeningitis

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