Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania

Author:

Mremi Alex12ORCID,Gnanamuttupulle Marianne23,Ntundu Shilanaiman Hilary3,Henke Oliver45,Chilonga Kondo23,Msuya David23

Affiliation:

1. Department of Pathology Kilimanjaro Christian Medical Centre Moshi Tanzania

2. Faculty of Medicine Kilimanjaro Christian Medical University College Moshi Tanzania

3. Department of General Surgery Kilimanjaro Christian Medical Centre Moshi Tanzania

4. Cancer Care Canter Kilimanjaro Christian Medical Centre Moshi Tanzania

5. Section Global Health, Institute for Hygiene and Public Health University Hospital Bonn Bonn Germany

Abstract

Key Clinical Message Describes a rare form of invasive breast cancer of no special type. Not a distinct morphological subtype. Characterized by dense lymphoid infiltrate, syncytial growth, pushing borders, and cells with high‐grade nuclei. Clinically aggressive but carries a better prognosis than other more frequent invasive breast carcinomas. AbstractInvasive breast carcinoma of no special type with medullary pattern (BCNST‐MP) is a rare form of breast tumor, accounting for less than 5% of all invasive breast carcinomas. Its diagnosis is based on histologic criteria. Historically, this tumor was known as medullary carcinoma. Poor morphological reproducibility led to re‐classification. Despite having an aggressive biological behavior, these tumors usually carry a better prognosis compared with other more frequent forms of invasive breast carcinomas. Herein, we present a case of BCNST‐MP in a 58‐year‐old African female, successfully treated in our institution through chemo‐radiation, hormonal therapy and surgery.

Publisher

Wiley

Subject

General Medicine

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