Can acetylcysteine ameliorate cisplatin‐induced toxicities and oxidative stress without decreasing antitumor efficacy? A randomized, double‐blind, placebo‐controlled trial involving patients with head and neck cancer-Reference-Cited by-同舟云学术

Can acetylcysteine ameliorate cisplatin‐induced toxicities and oxidative stress without decreasing antitumor efficacy? A randomized, double‐blind, placebo‐controlled trial involving patients with head and neck cancer

Published:2019-04-11 Issue:5 Volume:8 Page:2020-2030
ISSN:2045-7634
Container-title:Cancer Medicine
language:en
Short-container-title:Cancer Med

Author:

Visacri Marília B.¹,Quintanilha Júlia C. F.¹,Sousa Vanessa M.²,Amaral Laís S.¹,Ambrósio Rosiane¹,Calonga Luciane³,Curi Silvia F. B. B.³,Leme Mayra F.³,Chone Carlos T.³,Altemani João M. C.³,Mazzola Priscila G.²,Malaguti Carina¹,Vercesi Aníbal E.¹,Lima Carmen S. P.¹,Moriel Patricia²^ORCID

Affiliation:

1. School of Medical Sciences University of Campinas Campinas Brazil

2. Faculty of Pharmaceutical Sciences University of Campinas Campinas Brazil

3. Clinical Hospital University of Campinas Campinas Brazil

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Wiley

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cam4.2072

Reference46 articles.

1. Adverse drug reactions and kinetics of cisplatin excretion in urine of patients undergoing cisplatin chemotherapy and radiotherapy for head and neck cancer: a prospective study

2. Quality of life of patients with squamous cell carcinoma of the head and neck receiving high‐dose cisplatin chemotherapy and radiotherapy;Visacri MB;South Med J,2015

3. Cisplatin Induces a Mitochondrial-ROS Response That Contributes to Cytotoxicity Depending on Mitochondrial Redox Status and Bioenergetic Functions

4. Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation

5. Augmentation of transport for cisplatin‐glutathione adduct in cisplatin‐resistant cancer cells;Goto S;Cancer Res,1995

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