Affiliation:
1. Laboratory of Physiologically Active Compounds, Department of Medicinal Chemistry N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry Lavrentyev Avenue 9 630090 Novosibirsk Russia
Abstract
AbstractFor the first time, an effective method for the synthesis of spirocyclic camphor‐ and fenchone‐based 1,3,4‐oxadiazolines has been developed. The influence of the molecular structure of the terpene substrate on the reaction stereoselectivity was studied. The structural features of the target products were studied using NMR spectroscopy and X‐ray diffraction analysis. The proposed method allows obtaining of spirocyclic products with a wide structural diversity, stereoselectively and in good yields.
Funder
Ministry of Science and Higher Education of the Russian Federation
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Cited by
2 articles.
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