Synthesis of Diverse 4‐Pyrrolin‐2‐ones by Electrochemically Induced Dehydrogenative Regioselective Cyclization of 3‐Aza‐1,5‐dienes and 1,3‐Dicarbonyl Compounds-Reference-Cited by-同舟云学术

Synthesis of Diverse 4‐Pyrrolin‐2‐ones by Electrochemically Induced Dehydrogenative Regioselective Cyclization of 3‐Aza‐1,5‐dienes and 1,3‐Dicarbonyl Compounds

Published:2024-02-09 Issue:11 Volume:27 Page:
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur J Org Chem

Author:

Ji Xing¹,He Run¹,Shi Lou¹^ORCID,Sun Shaoguang²^ORCID,Liang Deqiang¹^ORCID

Affiliation:

1. Yunnan Key Laboratory of Metal-Organic Molecular Materials and Device School of Chemistry and Chemical Engineering Kunming University 2 Puxin Road Kunming, Yunnan Province 650214 P. R. China

2. Medical College Panzhihua University Donghua Street of East District Panzhihua, Sichuan province 617000 P. R. China

Abstract

AbstractA practical and mild electrochemical dehydrogenative regioselective cyclization method has been established for the synthesis of 4‐pyrrolin‐2‐ones using 3‐aza‐1,5‐dienes and 1,3‐dicarbonyl compounds as substrates. This protocol is catalyst‐free, metal‐free, and does not require oxidizing agents. It exhibits wide substrate compatibility and can be easily scaled up to the gram scale.

Funder

National Natural Science Foundation of China

Publisher

Wiley

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