4,4‐Difluorospiro[2.2]pentan‐1‐yl – A Fluorinated Substituent To Expand the Synthetic and Medicinal Chemists’ Toolbox-Reference-Cited by-同舟云学术

4,4‐Difluorospiro[2.2]pentan‐1‐yl – A Fluorinated Substituent To Expand the Synthetic and Medicinal Chemists’ Toolbox

Published:2022-09-12 Issue:40 Volume:2022 Page:
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur J Org Chem

Author:

Melnykov Kostiantyn P.¹²,Voloshyna Olena V.¹²,Vashchenko Bohdan V.¹²^ORCID,Demchuk Oleksandr P.¹³,Hryshchuk Oleksandr V.¹²^ORCID,Grygorenko Oleksandr O.¹²^ORCID

Affiliation:

1. Enamine Ltd. Chervonotkatska Street 78 Kyїv 02094 Ukraine

2. Taras Shevchenko National University of Kyїv Volodymyrska Street 60 Kyїv 01601 Ukraine

3. Institute of Organic Chemistry National Academy of Sciences of Ukraine Murmanska Street 5 Kyїv 02660 Ukraine

Funder

Enamine

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ejoc.202200863

Reference44 articles.

1. Conformational restriction: an effective tactic in 'follow-on'-based drug discovery

2. A. Mann inThe Practice of Medicinal Chemistry Elsevier 2008 pp. 363–379.

3. Spirocyclic Scaffolds in Medicinal Chemistry

4. On the origins of three-dimensionality in drug-like molecules

5. Optically Active Mesogenic Dispiro[2.0.2.1]Heptane Derivatives and their Unusual Physical Properties

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