Trimodular Solution‐Phase Protocol for Rapid Large‐Scale Synthesis of Hydrogen Bond Surrogate‐Constrained α‐Helicomimics
Author:
Affiliation:
1. Department of Organic Chemistry Indian Institute of Science Bangalore Karnataka 560012 India
Publisher
Wiley
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ejoc.202001359
Reference48 articles.
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2. The Hydrogen Bond Mimic Approach: Solid-Phase Synthesis of a Peptide Stabilized as an α-Helix with a Hydrazone Link
3. A Highly Stable Short α-Helix Constrained by a Main-Chain Hydrogen-Bond Surrogate
4. A Single α-Helical Turn Stabilized by Replacement of an Internal Hydrogen Bond with a Covalent Ethylene Bridge
5. A Single α-Helical Turn Stabilized by Replacement of an Internal Hydrogen Bond with a Covalent Ethylene Bridge
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1. Impact of Hydrogen‐Bond Surrogate Model on Helix Stabilization and Development of Protein‐Protein Interaction Inhibitors;ChemistrySelect;2023-03-09
2. α‐Helices propagating from stable nucleators exhibit unconventional thermal folding;FEBS Letters;2021-11-10
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