6‐Methylquinazolin‐4(3 <i>H</i> )‐one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of <i>in silico</i> Studies and Chemical Synthesis-Reference-Cited by-同舟云学术

6‐Methylquinazolin‐4(3 H )‐one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis

Published:2022-09-15 Issue:35 Volume:2022 Page:
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur J Org Chem

Author:

Colarusso Ester¹,Gazzillo Erica¹²,Boccia Eleonora¹²,Giordano Assunta¹³,Chini Maria Giovanna⁴,Bifulco Giuseppe¹^ORCID,Lauro Gianluigi¹^ORCID

Affiliation:

1. Department of Pharmacy University of Salerno Via Giovanni Paolo II 132 84084 Fisciano (SA) Italy

2. Ph.D. Program in Drug Discovery and Development University of Salerno Via Giovanni Paolo II 132 84084 Fisciano (SA) Italy

3. Institute of Biomolecular Chemistry (ICB) Consiglio Nazionale delle Ricerche (CNR) Via Campi Flegrei 34 80078 Pozzuoli (NA) Italy

4. Department of Biosciences and Territory University of Molise C.da Fonte Lappone 86090 Pesche (IS) Italy

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ejoc.202200868

Reference50 articles.

1. Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

2. The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins

4. Targeting BRD9 for Cancer Treatment: A New Strategy

5. Diverse Roles and Interactions of the SWI/SNF Chromatin Remodeling Complex Revealed Using Global Approaches

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