Metal‐ and Catalyst‐Free Synthesis of 2‐Substituted‐Phthalimides Using 2‐(Arenesulfonyl)Phthalimide as Key Reagents-Reference-Cited by-同舟云学术

Metal‐ and Catalyst‐Free Synthesis of 2‐Substituted‐Phthalimides Using 2‐(Arenesulfonyl)Phthalimide as Key Reagents

Published:2023-04-17 Issue:17 Volume:26 Page:
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur J Org Chem

Author:

Khalifa Abdalrahman¹,Giles Marco¹^ORCID,Ali Hamed I.²^ORCID,Mohamady Samy³⁴^ORCID

Affiliation:

1. Department of Chemistry Prairie View A&M University Prairie View TX 77446 USA

2. Irma Lerma Rangel School of Pharmacy Texas A&M Health Science Center Texas A&M University College Station TX 77843 USA

3. Pharmaceutical Chemistry Department Faculty of Pharmacy The British University in Egypt Cairo Egypt

4. Center of Drug Research and Development (CDRD) The British University in Egypt Cairo Egypt

Abstract

AbstractPhthalimide derivatives are important in medicinal chemistry, several phthalimidation methodologies have been developed. Here, we report a facile, metal‐free, and catalyst‐free method for the preparation of N‐phthalimides in good to excellent yield by reacting 2‐(arenesulfonyl)phthalimides with various amine substrates.

Funder

British University in Egypt

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

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