Affiliation:
1. College of Chemistry and Chemical Engineering Key Laboratory of Fuction-Oriented Porous Materials of Henan Province Luoyang Normal University Luoyang Henan 471934 P. R. China
2. College of Chemistry and Materials Science Key Laboratory of Chemical Biology of Hebei Province Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education State Key Laboratory of New Pharmaceutical Preparations and Excipients Hebei University Baoding Hebei 071002 P. R. China
Abstract
AbstractGiven the profound effect of fluorine‐containing groups in improving the chemical, physical, and biological properties of the parent compound, the fluorine‐containing groups were receiving increasing attention in the medicinal, pharmaceutical, agricultural, and material sciences. Unlike well‐developed trifluoromethylation and difluoromethylation reactions, the efficient and mild methods for rapid introduction of CF2Me are still underdeveloped, despite their important applications in pharmaceuticals and agrochemicals. This concept describes recent progress in difluoroethylation functionalization.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Hebei Province
Subject
Organic Chemistry,Physical and Theoretical Chemistry