Affiliation:
1. Department Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 China
2. Frontiers Science Center for Transformative Molecules and Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs Shanghai Jiao Tong University Shanghai 200240 China
Abstract
AbstractThis work showcases a novel visible‐light mediated allenylation protocol employing propargyl sulfides as a pioneering radical trapping methodology. A diverse array of substituted sulfonyl allenes were successfully synthesized under mild conditions with commendable levels of chemo‐ and regio‐selectivity. Mechanistically, this process entails the formation of sulfonyl radicals, their subsequent addition to alkynes, the subsequent elimination of S‐centered radicals, and Cl‐atom abstraction, thereby facilitating the propagation of this radical chain reaction.
Funder
National Natural Science Foundation of China
Fundamental Research Funds for the Central Universities
Program of Shanghai Academic Research Leader