Electrochemical Decarboxylative Addition of <i>N</i>‐Aryl Glycines to Enaminones: Access to C3‐Aminomethyl Chromones-Reference-Cited by-同舟云学术

Electrochemical Decarboxylative Addition of N‐Aryl Glycines to Enaminones: Access to C3‐Aminomethyl Chromones

Published:2024-05-17 Issue:28 Volume:27 Page:
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur J Org Chem

Author:

Han Siyang¹²,Fang Chengcheng¹²,Zhang Yaoge¹²,Li Sifeng¹³^ORCID,Huang Min¹,Wang Taimin¹,An Baigang²^ORCID,Cheng Bin¹²

Affiliation:

1. Institute of Marine Biomedicine Shenzhen Polytechnic University Shenzhen 518055 China

2. School of Chemical Engineering University of Science and Technology Liaoning Anshan 114051 China

3. Institute of Critical Materials for Integrated Circuits Shenzhen Polytechnic University Shenzhen 518055 China

Abstract

AbstractAn electrochemical decarboxylative addition of N‐substituted glycines to enaminones has been developed and conducted under oxidant‐, catalyst‐, and light‐free conditions in acetonitrile at room temperature by using electron as the traceless oxidant, which provided a green approach to access C3‐aminomethyl chromones. The resulting products were formed through radical addition/oxidation/cyclization or electrophilic addition/cyclization pathway and could act as valuable building blocks to construct polysubstituted pyrimidine derivatives.

Funder

Shenzhen Polytechnic

Science, Technology and Innovation Commission of Shenzhen Municipality

Publisher

Wiley

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