Affiliation:
1. School of Biotechnology and Health Sciences Wuyi University Jiangmen 529020 China
2. Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic University Hong Kong 00000 China
Abstract
AbstractThis study describes a method of synthesising pyridine, quinoline, and isoquinoline ketones using 2‐halogenated N‐heterocycles as the starting materials under mild reaction conditions. Considering the significance of pyridones in organic chemistry, developing novel, green synthetic strategies is highly desirable. The reaction employs H2O as the solvent and source of O, rendering it green, and it is simple to execute, with a broad substrate scope and an excellent functional group tolerance.
Funder
National Natural Science Foundation of China
Subject
Organic Chemistry,Physical and Theoretical Chemistry