Preparation and Aldol Couplings of 3(2H)‐Furanones: Stereoselective Synthesis of the C8‐C22 Fragment of Tuscoron A-Reference-Cited by-同舟云学术

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Preparation and Aldol Couplings of 3(2H)‐Furanones: Stereoselective Synthesis of the C8‐C22 Fragment of Tuscoron A

Published:2024-07-24 Issue:32 Volume:27 Page:
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur J Org Chem

Author:

Bieber Michelle Fernandez¹²,Gao Xin¹,Wagner Raphael¹,Holzapfel Björn¹³,Tomczyk Pascal¹,Menche Dirk¹^ORCID

Affiliation:

1. Kekulé-Institut für Organische Chemie und Biochemie Rheinische Friedrich-Wilhelms-Universität Bonn Gerhard-Domagk-Str. 1 53121 Bonn Germany

2. Present address: Google D-80636 Munich Germany

3. Present address: Pfizer D-79108 Freiburg im Breisgau Germany

Abstract

AbstractVarious strategies for synthesis and stereroselective aldol coupling of furan‐3(2H)‐ones were evaluated that eventually enabled a highly stereroselective synthesis of the C8‐C22 fragment of tuscoron A.

Funder

Deutsche Forschungsgemeinschaft

China Scholarship Council

Publisher

Wiley

Reference41 articles.

1. Tuscolid and Tuscoron A and B: Isolation, Structural Elucidation and Studies on the Biosynthesis of Novel Furan-3(2H)-one-Containing Metabolites from the MyxobacteriumSorangium Cellulosum

3. The chemistry of gliding bacteria

4. Myxobacterial secondary metabolites: bioactivities and modes-of-action

5. Natural products from myxobacteria: novel metabolites and bioactivities

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