Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones-Reference-Cited by-同舟云学术

Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones

Published:2012-05 Issue:5 Volume:14 Page:299-315
ISSN:1099-498X
Container-title:The Journal of Gene Medicine
language:en
Short-container-title:J Gene Med

Author:

Hutson Thomas H.¹,Foster Edmund¹,Dawes John M.¹,Hindges Robert²,Yáñez-Muñoz Rafael J.³,Moon Lawrence D. F.¹

Affiliation:

1. Neurorestoration Group, Wolfson Centre for Age-Related Diseases; King's College London; Guy's Campus; London; UK

2. MRC Centre for Developmental Neurobiology; King's College London; Guy's Campus; London; UK

3. Centre for Biomedical Sciences, School of Biological Sciences; Royal Holloway-University of London; Egham; Surrey; UK

Publisher

Wiley

Subject

Genetics(clinical),Drug Discovery,Genetics,Molecular Biology,Molecular Medicine

Reference91 articles.

1. Intrinsic neuronal regulation of axon and dendrite growth;Goldberg;Curr Opin Neurobiol,2004

2. Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway;Park;Science (New York, NY),2008

3. KLF family members regulate intrinsic axon regeneration ability;Moore;Science (New York, NY),2009

4. Corticospinal neurons up-regulate a range of growth-associated genes following intracortical, but not spinal, axotomy;Mason;Eur J Neurosci,2003

5. A new millenium for spinal cord regeneration: growth-associated genes;Bulsara;Spine,2002

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Reducing LncRNA-5657 expression inhibits the brain inflammatory reaction in septic rats;Neural Regeneration Research;2021

2. Revisiting gene delivery to the brain: silencing and editing;Biomaterials Science;2021

3. Ex Vivo Rat Transected Spinal Cord Slices as a Model to Assess Lentiviral Vector Delivery of Neurotrophin-3 and Short Hairpin RNA against NG2;Biology;2020-03-15

4. Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing;Molecular Therapy - Methods & Clinical Development;2017-06

5. The application of CRISPR technology to high content screening in primary neurons;Molecular and Cellular Neuroscience;2017-04