Glycogen Synthase Kinase 3 Inhibition Stimulates Human Cartilage Destruction and Exacerbates Murine Osteoarthritis
Author:
Affiliation:
1. University of the West of Scotland, Paisley Campus; Paisley UK
2. Newcastle University; Newcastle-upon-Tyne UK
Funder
Arthritis Research UK
Publisher
Wiley
Subject
Immunology,Rheumatology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/art.38681/fullpdf
Reference57 articles.
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3. Increased expression of metalloproteinase-8 and -13 on articular cartilage in a rat immobilized knee model;Ando;Tohoku J Exp Med,2009
4. Expression of membrane-type 1 matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage;Imai;Am J Pathol,1997
5. Interleukin-1 in combination with oncostatin M up-regulates multiple genes in chondrocytes: implications for cartilage destruction and repair;Barksby;Arthritis Rheum,2006
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