Population pharmacokinetics of empagliflozin, a sodium glucose cotransporter 2 inhibitor, in patients with type 2 diabetes

Author:

Riggs Matthew M.1,Staab Alexander2,Seman Leo3,MacGregor Thomas R.3,Bergsma Timothy T.1,Gastonguay Marc R.1,Macha Sreeraj3

Affiliation:

1. Metrum Research Group LLC; Tariffville; CT; USA

2. Boehringer Ingelheim Pharma GmbH & Co. KG; Biberach; Germany

3. Boehringer Ingelheim Pharmaceuticals, Inc.; Ridgefield; CT; USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference33 articles.

1. International Diabetes Federation Diabetes Atlas Fourth Edition. Prevalence estimates of diabetes mellitus (DM), 2010. International Diabetes Federation, 2010. Available at http://www.diabetesatlas.com/content/prevalence-estimates-diabetes-mellitus-dm-2010

2. Molecular understanding of hyperglycemia's adverse effects for diabetic complications;Sheetz;JAMA.,2002

3. Impact of diabetes on vasculature: focus on nervous system;Skljarevski;Curr Diabetes Rev.,2005

4. Cellular and molecular mechanisms of vascular injury in diabetes-part I: pathways of vascular disease in diabetes;Madonna;Vasc Pharmacol.,2011

5. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33);UK Prospective Diabetes Study (UKPDS) Group;Lancet.,1998

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