1. Laboratory of Pharmaceutics; School of Pharamcy, Nihon University; 7-7-1 Narashinodai Funabashi Chiba 274-8555 Japan
2. Laboratory of Clinical Pharmacokinetics; School of Pharamcy, Nihon University; 7-7-1 Narashinodai Funabashi Chiba 274-8555 Japan
3. Nihon Pharmaceutical University; Kita-adachi Saitama 362-0806 Japan
4. Department of Molecular Pharmaceutics; Meiji Pharmaceutical University; Kiyose Tokyo 204-8588 Japan