Centrosome and spindle pole microtubules are main targets of a fluorescent taxoid inducing cell death

Author:

Abal Miguel,Souto André A.,Amat-Guerri Francisco,Acuña A. Ulises,Andreu Jose M.,Barasoain Isabel

Funder

Fundación Científica de la Asociació Española contra el Cancer

Direccion General de Investigación

Comunidad Autonoma de Madrid

Publisher

Wiley

Subject

Cell Biology,Structural Biology

Reference78 articles.

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2. Low resolution structure of microtubules in solution. Synchrotron X-ray scattering and electron microscopy of taxol-induced microtubules assembled from purified tubulin in comparison with glycerol- and Map-induced microtubules;Andreu;J Mol Biol,1992

3. Solution structure of Taxotere-induced microtubules to 3 nm resolution. The change in protofilament number is linked to the binding of the taxol side chain;Andreu;J Biol Chem,1994

4. Use of a photoactivable taxol analogue to identify unique cellular targets in murine macrophages: identification of murine CD18 as a major taxol-binding protein and a role for Mac-1 in taxol-induced gene expression;Bhat;J Immunol,1999

5. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers;Bischoff;EMBO J,1998

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