Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study

Author:

Brunner Clair12,Davies Neil M.12,Martin Richard M.123,Eeles Rosalind45,Easton Doug6,Kote-Jarai Zsofia4,Al Olama Ali Amin6,Benlloch Sara6,Muir Kenneth7,Giles Graham89,Wiklund Fredrik10,Gronberg Henrik10,Haiman Christopher A.11,Schleutker Johanna1213,Nordestgaard Børge G.14,Travis Ruth C.15,Neal David1617,Donovan Jenny1,Hamdy Freddie C.18,Pashayan Nora1920,Khaw Kay-Tee21,Stanford Janet L.2223,Blot William J.24,Thibodeau Stephen25,Maier Christiane2627,Kibel Adam S.2829,Cybulski Cezary30,Cannon-Albright Lisa31,Brenner Hermann323334,Park Jong35,Kaneva Radka36,Batra Jyotsna37,Teixeira Manuel R.38,Pandha Hardev39,Zuccolo Luisa12,

Affiliation:

1. School of Social and Community Medicine; University of Bristol; Bristol United Kingdom

2. MRC/University of Bristol Integrative Epidemiology Unit, University of Bristol; Bristol United Kingdom

3. The NIHR Bristol Nutrition Biomedical Research Unit; University Hospitals Bristol NHS Foundation Trust and the University of Bristol; Bristol United Kingdom

4. The Institute of Cancer Research; London SM2 5NG United Kingdom

5. Royal Marsden NHS Foundation Trust; London SW3 6JJ United Kingdom

6. Strangeways Laboratory, Department of Public Health and Primary Care; Centre for Cancer Genetic Epidemiology, University of Cambridge; Worts Causeway Cambridge United Kingdom

7. Institute of Population Health, University of Manchester; Manchester United Kingdom

8. The Cancer Council Victoria; Cancer Epidemiology Centre; 1 Rathdowne Street Carlton Vic Australia

9. Centre for Molecular, Environmental, Genetic and Analytic Epidemiology; The University of Melbourne; Vic Australia

10. Department of Medical Epidemiology and Biostatistics; Karolinska Institute; Stockholm Sweden

11. Department of Preventive Medicine, Keck School of Medicine; University of Southern California/Norris Comprehensive Cancer Center; Los Angeles CA

12. Department of Medical Biochemistry and Genetics; University of Turku; Turku Finland

13. Institute of Biomedical Technology/BioMediTech, University of Tampere and FimLab Laboratories; Tampere Finland

14. Department of Clinical Biochemistry; Herlev Hospital, Copenhagen University Hospital; Herlev Ringvej 75 DK-2730 Herlev Denmark

15. Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine; University of Oxford; Oxford United Kingdom

16. Surgical Oncology (Uro-Oncology: S4); University of Cambridge, Box 279, Addenbrooke's Hospital; Hills Road Cambridge United Kingdom

17. Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre; Cambridge United Kingdom

18. Nuffield Department of Surgery; University of Oxford; Oxford United Kingdom

19. Strangeways Laboratory, Department of Oncology; Centre for Cancer Genetic Epidemiology, University of Cambridge; Worts Causeway Cambridge United Kingdom

20. Department of Applied Health Research; University College London; 1-19 Torrington Place London WC1E 7HB United Kingdom

21. Cambridge Institute of Public Health, University of Cambridge; Forvie Site Robinson Way Cambridge CB2 0SR United Kingdom

22. Division of Public Health Sciences; Fred Hutchinson Cancer Research Center; Seattle WA

23. Department of Epidemiology, School of Public Health; University of Washington; Seattle WA

24. International Epidemiology Institute; 1455 Research Blvd, Suite 550 Rockville MD

25. Mayo Clinic; Rochester MN

26. Department of Urology; University Hospital Ulm; Germany

27. Institute of Human Genetics University Hospital Ulm; Germany

28. Brigham and Women's Hospital/Dana-Farber Cancer Institute; 45 Francis Street-ASB II-3 Boston MA

29. Washington University; St Louis MO

30. Department of Genetics and Pathology; International Hereditary Cancer Center, Pomeranian Medical University; Szczecin Poland

31. Division of Genetic Epidemiology, Department of Medicine; University of Utah School of Medicine, Salt Lake City, UT

32. Division of Clinical Epidemiology and Aging Research; German Cancer Research Center (DKFZ); Heidelberg Germany

33. Division of Preventive Oncology; German Cancer Research Center (DKFZ); Heidelberg Germany

34. German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ); Heidelberg, Germany

35. Division of Cancer Prevention and Control; H. Lee Moffitt Cancer Center; 12902 Magnolia Dr Tampa FL

36. Department of Medical Chemistry and Biochemistry, Molecular Medicine Center; Medical University Sofia; 2 Zdrave St Sofia 1431 Bulgaria

37. Australian Prostate Cancer Research Centre-Qld, Institute of Health and Biomedical Innovation and Schools of Life Science and Public Health, Queensland University of Technology; BNE Australia

38. Department of Genetics; Portuguese Oncology Institute, Porto, Portugal and Biomedical Sciences Institute (ICBAS), Porto University; Porto Portugal

39. The University of Surrey; Guildford Surrey GU2 7XH United Kingdom

Funder

UK MRC Special Training Fellowship

UK MRC Population Health Scientist fellowship

UK MRC

University of Bristol

The European Commission's Seventh Framework Programme

Cancer Research UK

National Institutes of Health

National Institute of Health (NIH) Cancer Post-Cancer GWAS

Canadian Department of Defence

UK Health Technology Assessment (HTA) Programme of the NIH Research

National Cancer Research Institute (Department of Health, the Medical Research Council and Cancer Research UK)

Publisher

Wiley

Subject

Cancer Research,Oncology

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