The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine

Author:

Liu Angen,Yoshioka Ken-ichi,Salerno Vincenzo,Hsieh Peggy

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference39 articles.

1. 5-Fluorouracil incorporated into DNA is excised by the Smug1 DNA glycosylase to reduce drug cytotoxicity;An;Cancer Res,2007

2. Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts;Andersen;Carcinogenesis,2005

3. MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1;Bellacosa;Proc Natl Acad Sci USA,1999

4. Microsatellite instability and colorectal cancer prognosis;Benatti;Clin Cancer Res,2005

5. Selective radiosensitization of drug-resistant MutS homologue-2 (MSH2) mismatch repair-deficient cells by halogenated thymidine (dThd) analogues: Msh2 mediates dThd analogue DNA levels and the differential cytotoxicity and cell cycle effects of the dThd analogues and 6-thioguanine;Berry;Cancer Res,2000

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